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Prafulla C Gokhale Selected Research

LY3214996

1/2021ERK Inhibitor LY3214996-Based Treatment Strategies for RAS-Driven Lung Cancer.

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Prafulla C Gokhale Research Topics

Disease

50Neoplasms (Cancer)
01/2024 - 11/2002
11Lung Neoplasms (Lung Cancer)
11/2023 - 05/2011
6Carcinoma (Carcinomatosis)
12/2023 - 05/2004
4Merkel Cell Carcinoma
11/2023 - 01/2020
4Glioblastoma (Glioblastoma Multiforme)
01/2023 - 02/2016
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 01/2020
3Bites and Stings (Sting)
01/2024 - 10/2022
3Malignant Mesothelioma
10/2022 - 12/2020
3Breast Neoplasms (Breast Cancer)
01/2007 - 05/2004
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2023 - 01/2020
2Rhabdoid Tumor (Rhabdoid Tumors)
01/2020 - 01/2019
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2018 - 12/2017
2Pancreatic Neoplasms (Pancreatic Cancer)
01/2012 - 03/2004
1Wilms Tumor (Wilm's Tumor)
04/2024
1Leiomyosarcoma
09/2023
1Sarcoma (Soft Tissue Sarcoma)
09/2023
1Mitochondrial Diseases (Mitochondrial Disease)
10/2022
1Neuroendocrine Tumors (Neuroendocrine Tumor)
10/2022
1Neuroendocrine Carcinoma
10/2022
1Edema (Dropsy)
01/2021
1Brain Neoplasms (Brain Tumor)
01/2021
1Glioma (Gliomas)
01/2021
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2021
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2020
1Skin Neoplasms (Skin Cancer)
01/2020
1Medullary Carcinoma
12/2019

Drug/Important Bio-Agent (IBA)

12Proteins (Proteins, Gene)FDA Link
01/2023 - 11/2002
8Antisense OligonucleotidesIBA
01/2009 - 03/2004
7LErafAONIBA
01/2009 - 11/2002
6Tyrosine Kinase InhibitorsIBA
11/2022 - 01/2020
6Phosphotransferases (Kinase)IBA
01/2022 - 03/2011
4Immune Checkpoint InhibitorsIBA
01/2024 - 02/2016
4Oncogene Proteins (Oncogene Protein)IBA
12/2023 - 01/2020
4Biomarkers (Surrogate Marker)IBA
01/2023 - 05/2011
4ErbB Receptors (EGF Receptor)IBA
01/2022 - 01/2020
4Liposomes (Liposome)IBA
01/2009 - 03/2004
3Doxorubicin (Adriamycin)FDA LinkGeneric
04/2024 - 05/2004
3ChromatinIBA
12/2023 - 01/2021
3Messenger RNA (mRNA)IBA
09/2021 - 03/2006
3Mechanistic Target of Rapamycin Complex 1IBA
01/2021 - 03/2011
3Small Interfering RNA (siRNA)IBA
01/2019 - 01/2009
3OligonucleotidesIBA
01/2007 - 05/2004
2DNA (Deoxyribonucleic Acid)IBA
01/2024 - 09/2023
2InterferonsIBA
01/2024 - 11/2023
2Histones (Histone)IBA
12/2023 - 01/2019
2LigandsIBA
10/2022 - 02/2016
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2022 - 01/2020
2Tumor Viral Antigens (Large T Antigen)IBA
01/2022 - 01/2020
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2021 - 01/2021
2RNA (Ribonucleic Acid)IBA
01/2021 - 01/2021
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2021 - 02/2006
2UbiquitinIBA
01/2020 - 12/2017
2Therapeutic UsesIBA
01/2019 - 05/2004
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
12/2018 - 01/2009
2Sirolimus (Rapamycin)FDA Link
08/2011 - 11/2006
2Mechanistic Target of Rapamycin Complex 2IBA
08/2011 - 03/2011
2Antineoplastic Agents (Antineoplastics)IBA
08/2011 - 10/2010
23- (8- amino- 1- (2- phenylquinolin- 7- yl)imidazo(1,5- a)pyrazin- 3- yl)- 1- methylcyclobutanolIBA
05/2011 - 10/2010
1Programmed Cell Death 1 ReceptorIBA
05/2024
1Exonucleases (3' 5' Exonuclease)IBA
05/2024
1Nucleic AcidsIBA
01/2024
1exodeoxyribonuclease IIBA
01/2024
1tazemetostatIBA
12/2023
1Enhancer of Zeste Homolog 2 ProteinIBA
12/2023
1B7-H1 AntigenIBA
11/2023
1Aurora Kinase AIBA
11/2023
1pyrvinium (Vankin)FDA Link
11/2023
1Eukaryotic Initiation Factor-4F (EIF4F)IBA
01/2023
1Pemetrexed (MTA)FDA Link
11/2022
1PalmitatesIBA
10/2022
1Adenosine Monophosphate (AMP)IBA
10/2022
1Polycomb Repressive Complex 2IBA
10/2022
1Viral ProteinsIBA
01/2022
1capmatinibIBA
01/2022
1merestinibIBA
01/2022
1Protein Isoforms (Isoforms)IBA
01/2022
1QuinazolinonesIBA
01/2022
1milademetanIBA
01/2022
1Histone Deacetylase InhibitorsIBA
11/2021
1PanobinostatIBA
11/2021
1LY3023414IBA
01/2021
1LY3214996IBA
01/2021
1Adenosine Triphosphate (ATP)IBA
01/2021
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2021
1abemaciclibIBA
01/2021
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2021
1Natural Killer Cell ReceptorsIBA
01/2021
1Histone DemethylasesIBA
01/2021
1Atovaquone (Mepron)FDA Link
12/2020
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
12/2020
1monomethyl auristatin EIBA
03/2020
1Immunoconjugates (Immunoconjugate)IBA
03/2020
1NEO2734IBA
01/2020
1HomoharringtonineIBA
01/2020
1Ligases (Synthetase)IBA
01/2020
1Proteasome InhibitorsIBA
12/2019

Therapy/Procedure

13Therapeutics
01/2024 - 01/2007
6Immunotherapy
11/2023 - 01/2021
3Drug Therapy (Chemotherapy)
09/2023 - 03/2004
2Radiotherapy
01/2021 - 02/2006